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Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection

Several molecular datasets have been recently compiled to characterize the activity of SARS-CoV-2 within human cells. Here we extend computational methods to integrate several different types of sequence, functional and interaction data to reconstruct networks and pathways activated by the virus in...

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Dettagli Bibliografici
Pubblicato in:bioRxiv
Autori principali: Ding, Jun, Lugo-Martinez, Jose, Yuan, Ye, Huang, Jessie, Hume, Adam J., Suder, Ellen L., Mühlberger, Elke, Kotton, Darrell N., Bar-Joseph, Ziv
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574259/
https://ncbi.nlm.nih.gov/pubmed/33083801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.01.127589
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