Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice

BACKGROUND: Gut dysbiosis due to the adverse effects of antibiotics affects outcomes of lung infection. Previous murine models relied on significant depletion of both gut and lung microbiota, rendering the analysis of immune gut-lung cross-talk difficult. Here, we study the effects of antibiotic-ind...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Dessein, Rodrigue, Bauduin, Marvin, Grandjean, Teddy, Le Guern, Rémi, Figeac, Martin, Beury, Delphine, Faure, Karine, Faveeuw, Christelle, Guery, Benoit, Gosset, Philippe, Kipnis, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7574210/
https://ncbi.nlm.nih.gov/pubmed/33076936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03320-8
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