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Transformation from adenocarcinoma to squamous cell carcinoma associated with long-term administration of EGFR-TKIs
Although patients with non-small cell lung cancer exhibiting EGFR mutations generally respond to tyrosine kinase inhibitors (TKIs), the majority of patients acquire resistance ~1 year after treatment. EGFR T790M mutations, MET or HER2 amplifications and phenotypic transformations contribute to the m...
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| Publicado no: | Mol Clin Oncol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7574163/ https://ncbi.nlm.nih.gov/pubmed/33093956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2020.2152 |
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