Efficacy and mechanism of combination of oxaliplatin with PKM2 knockdown in colorectal cancer

M2 isomer of pyruvate kinase (PKM2), a key enzyme in aerobic glycolysis, is closely related to cancer development and progression. Suppression of PKM2 exhibits synergistic effects with docetaxel in lung cancer, but the therapeutic potential in colorectal cancer (CRC) is unclear. The aim of the prese...

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Detaylı Bibliyografya
Yayımlandı:Oncol Lett
Asıl Yazarlar: Yin, Chenxi, Lu, Wenhua, Ma, Mingzhe, Yang, Qiong, He, Wenzhuo, Hu, Yumin, Xia, Liangping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2020
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573921/
https://ncbi.nlm.nih.gov/pubmed/33093921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12175
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