Dual Host-Intracellular Parasite Transcriptome of Enucleated Cells Hosting Leishmania amazonensis: Control of Half-Life of Host Cell Transcripts by the Parasite

Enucleated cells or cytoplasts (cells whose nucleus is removed in vitro) represent an unexplored biological model for intracellular infection studies due to the abrupt interruption of nuclear processing and new RNA synthesis by the host cell in response to pathogen entry. Using enucleated fibroblast...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Orikaza, Cristina M., Pessoa, Carina C., Paladino, Fernanda V., Florentino, Pilar T. V., Barbiéri, Clara L., Goto, Hiro, Ramos-Sanchez, Eduardo Milton, Franco da Silveira, José, Rabinovitch, Michel, Mortara, Renato A., Real, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573452/
https://ncbi.nlm.nih.gov/pubmed/32817329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00261-20
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