Involvement of CXCL1/CXCR2 During Microglia Activation Following Inflammation-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Rats

Background: Microglia are key mediators of inflammation during perinatal brain injury. As shown experimentally after inflammation-sensitized hypoxic ischemic (HI) brain injury, microglia are activated into a pro-inflammatory status 24 h after HI involving the NLRP3 inflammasome pathway. The chemokin...

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Dettagli Bibliografici
Pubblicato in:Front Neurol
Autori principali: Serdar, Meray, Kempe, Karina, Herrmann, Ralf, Picard, Daniel, Remke, Marc, Herz, Josephine, Bendix, Ivo, Felderhoff-Müser, Ursula, Sabir, Hemmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neurology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573390/
https://ncbi.nlm.nih.gov/pubmed/33123073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.540878
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