Mesenchymal Stromal Cells’ Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go?

Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by the expansion of the cytosine-adenine-guanine (CAG) repeat. This mutation encodes extended glutamine (Q) tract in the disease protein, resulting in the alteration of its conformation/physiological role and...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Barros, Inês, Marcelo, Adriana, Silva, Teresa P., Barata, João, Rufino-Ramos, David, Pereira de Almeida, Luís, Miranda, Catarina O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cellular Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573388/
https://ncbi.nlm.nih.gov/pubmed/33132851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.584277
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