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Bucco-Adhesive Film as a Pediatric Proper Dosage Form for Systemic Delivery of Propranolol Hydrochloride: In-vitro and in-vivo Evaluation

OBJECTIVE: To formulate and assess bucco-adhesive films of propranolol hydrochloride for pediatric use. METHODS: Different films were formulated adopting mucin, polyvinyl alcohol, chitosan and carbopol. A drug/polymer compatibility study was conducted adopting differential scanning calorimetry and F...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Mohamad, Soad A, Salem, Hesham, Yassin, Heba A, Mansour, Heba F
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573323/
https://ncbi.nlm.nih.gov/pubmed/33116415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S267317
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