The binding mechanism of the virulence factor Streptococcus suis adhesin P subtype to globotetraosylceramide is associated with systemic disease

Streptococcus suis is part of the pig commensal microbiome but strains can also be pathogenic, causing pneumonia and meningitis in pigs as well as zoonotic meningitis. According to genomic analysis, S. suis is divided into asymptomatic carriage, respiratory and systemic strains with distinct genomic...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Madar Johansson, Miralda, Bélurier, Eva, Papageorgiou, Anastassios C., Sundin, Anders P., Rahkila, Jani, Kallonen, Teemu, Nilsson, Ulf J., Maatsola, Santeri, Nyholm, Thomas K. M., Käpylä, Jarmo, Corander, Jukka, Leino, Reko, Finne, Jukka, Teneberg, Susann, Haataja, Sauli
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7573278/
https://ncbi.nlm.nih.gov/pubmed/32796033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014818
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