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The crosstalk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism
Mitochondria supply ATP essential for synaptic transmission. Neurons face exceptional challenges in maintaining energy homeostasis at synapses. Regulation of mitochondrial trafficking and anchoring is critical for neurons to meet increased energy consumption during sustained synaptic activity. Howev...
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| Published in: | Nat Metab |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572785/ https://ncbi.nlm.nih.gov/pubmed/33020662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-00289-0 |
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