Severity of Topiramate-Related Working Memory Impairment is Modulated by Plasma Concentration and Working Memory Capacity

Drug side effects which impair cognition can lead to diminished quality of life and discontinuation of therapy. Topiramate is an antiepileptic drug which elicits cognitive deficits more frequently than other antiepileptic drugs, impairing multiple cognitive domains including language, attention, and...

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Veröffentlicht in:J Clin Pharmacol
Hauptverfasser: Callisto, Samuel P., Illamola, Sílvia M., Birnbaum, Angela K., Barkley, Christopher M., Bathena, Sai Praneeth R., Leppik, Ilo E., Marino, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572737/
https://ncbi.nlm.nih.gov/pubmed/32297992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1611
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