Patient-Centered Outcomes in ARIEL3, a Phase III, Randomized, Placebo-Controlled Trial of Rucaparib Maintenance Treatment in Patients With Recurrent Ovarian Carcinoma

PURPOSE: To investigate quality-adjusted progression-free survival (QA-PFS) and quality-adjusted time without symptoms or toxicity (Q-TWiST) in a post hoc exploratory analysis of the phase III ARIEL3 study of rucaparib maintenance treatment versus placebo. PATIENTS AND METHODS: Patients with platinu...

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Vydáno v:J Clin Oncol
Hlavní autoři: Oza, Amit M., Lorusso, Domenica, Aghajanian, Carol, Oaknin, Ana, Dean, Andrew, Colombo, Nicoletta, Weberpals, Johanne I., Clamp, Andrew R., Scambia, Giovanni, Leary, Alexandra, Holloway, Robert W., Gancedo, Margarita Amenedo, Fong, Peter C., Goh, Jeffrey C., O’Malley, David M., Armstrong, Deborah K., Banerjee, Susana, García-Donas, Jesus, Swisher, Elizabeth M., Cella, David, Meunier, Juliette, Goble, Sandra, Cameron, Terri, Maloney, Lara, Mörk, Ann-Christin, Bedel, Josh, Ledermann, Jonathan A., Coleman, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571791/
https://ncbi.nlm.nih.gov/pubmed/32840418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.03107
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