Clinical performance and utility of a comprehensive next-generation sequencing DNA panel for the simultaneous analysis of variants, TMB and MSI for myeloid neoplasms

The extensively employed limited-gene coverage NGS panels lead to clinically inadequate molecular profiling of myeloid neoplasms. The aim of the present investigation was to assess performance and clinical utility of a comprehensive DNA panel for myeloid neoplasms. Sixty-one previously well characte...

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Publicat a:PLoS One
Autors principals: Sahajpal, Nikhil Shri, Mondal, Ashis K., Ananth, Sudha, Njau, Allan, Ahluwalia, Pankaj, Jones, Kimya, Ahluwalia, Meenakshi, Okechukwu, Nwogbo, Savage, Natasha M., Kota, Vamsi, Rojiani, Amyn M., Kolhe, Ravindra
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571681/
https://ncbi.nlm.nih.gov/pubmed/33075099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0240976
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