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Randomized, double-blind, placebo-controlled, crossover study of the effects of repeated-dose caffeine on neurobehavioral performance during 48 h of total sleep deprivation

RATIONALE: Caffeine is widely used as a countermeasure against neurobehavioral impairment during sleep deprivation. However, little is known about the pharmacodynamic profile of caffeine administered repeatedly during total sleep deprivation. OBJECTIVES: To investigate the effects of repeated caffei...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Hansen, Devon A., Ramakrishnan, Sridhar, Satterfield, Brieann C., Wesensten, Nancy J., Layton, Matthew E., Reifman, Jaques, Van Dongen, Hans P.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571542/
https://ncbi.nlm.nih.gov/pubmed/30539266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-5140-0
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