Metformin prevents the development of monocrotaline-induced pulmonary hypertension by decreasing serum levels of big endothelin-1

Pulmonary hypertension (PH) is a disease with poor prognosis, and it is characterized by the progressive elevation of pulmonary vascular resistance and pressure. Various factors are associated with the pathology of PH, including AMP-activated protein kinase (AMPK) deficiency. The present study aimed...

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Vydáno v:Exp Ther Med
Hlavní autoři: Yoshida, Tomohiko, Matsuura, Katsuhiro, Goya, Seijirow, Ma, Danfu, Shimada, Kazumi, Kitpipatkun, Pitipat, Namiki, Ryosuke, Uemura, Akiko, Suzuki, Kazuhiko, Tanaka, Ryou
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571338/
https://ncbi.nlm.nih.gov/pubmed/33093887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9278
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