Protein Phosphatase 2A and Clathrin-Mediated Endocytosis Facilitate Robust Melanopsin Light Responses and Resensitization

PURPOSE: Intrinsically photosensitive retinal ganglion cells (ipRGCs) that express the visual pigment melanopsin regulate non-image-forming visual tasks, such as circadian photoentrainment and pupil constriction, as well as contrast detection for image formation. Sustained ipRGC function throughout...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Valdez-Lopez, Juan C., Gebreegziabher, Meheret, Bailey, Robin J., Flores, Jair, Awotunde, Olanike, Burnett, Thomas, Robinson, Phyllis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2020
Témata:
Biochemistry and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571330/
https://ncbi.nlm.nih.gov/pubmed/33049058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.12.10
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