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Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS

Dalbavancin is a novel semisynthetic glycopeptide antibiotic that comprises multiple homologs and isomers of similar polarities. However, pharmacokinetic studies have only analyzed the primary components of dalbavancin, namely B(0) and B(1). In this study, an ultra-high-performance liquid chromatogr...

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Publicado en:Molecules
Main Authors: Zhu, Difeng, Ping, Li, Hong, Yawen, Shen, Jiale, Weng, Qinjie, He, Qiaojun
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570859/
https://ncbi.nlm.nih.gov/pubmed/32911715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184100
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