Nalaganje...

Bcr-Abl Allosteric Inhibitors: Where We Are and Where We Are Going to

The fusion oncoprotein Bcr-Abl is an aberrant tyrosine kinase responsible for chronic myeloid leukemia and acute lymphoblastic leukemia. The auto-inhibition regulatory module observed in the progenitor kinase c-Abl is lost in the aberrant Bcr-Abl, because of the lack of the N-myristoylated cap able...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Carofiglio, Francesca, Trisciuzzi, Daniela, Gambacorta, Nicola, Leonetti, Francesco, Stefanachi, Angela, Nicolotti, Orazio
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570842/
https://ncbi.nlm.nih.gov/pubmed/32937901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25184210
Oznake: Označite
Brez oznak, prvi označite!