Management of a patient with mantle cell lymphoma who developed severe neurotoxicity after chimeric antigen receptor T-cell therapy in ZUMA-2

Cerebral edema following chimeric antigen receptor (CAR) T-cell therapy can be fatal. ZUMA-2 is a pivotal phase 2, multicenter study evaluating KTE-X19, an autologous anti-CD19 CAR T-cell therapy, in relapsed/refractory mantle cell lymphoma. We describe a 65-year-old patient in ZUMA-2 who developed...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Wang, Michael, Jain, Preetesh, Chi, T Linda, Chen, Sheree E, Heimberger, Amy, Weathers, Shiao-Pei, Zheng, Lianqing, Rao, Arati V, Rossi, John M
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570235/
https://ncbi.nlm.nih.gov/pubmed/33067318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001114
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