Neuroprotective effects of verbascoside against Alzheimer’s disease via the relief of endoplasmic reticulum stress in Aβ-exposed U251 cells and APP/PS1 mice

BACKGROUND: Endoplasmic reticulum (ER) stress is involved in the progression of Alzheimer’s disease (AD). Verbascoside (VB), an active phenylethanoid glycoside that was first isolated from Verbascum sinuatum (the wavyleaf mullein), possesses anti-inflammatory, antioxidative, and anti-apoptotic effec...

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Pubblicato in:J Neuroinflammation
Autori principali: Wang, Chunyue, Cai, Xueying, Wang, Ruochen, Zhai, Siyu, Zhang, Yongfeng, Hu, Wenji, Zhang, Yizhi, Wang, Di
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7570123/
https://ncbi.nlm.nih.gov/pubmed/33070776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01976-1
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