Protocol of a prospective, multicentre phase I study to evaluate the safety, tolerability and preliminary efficacy of the bispecific PSMAxCD3 antibody CC-1 in patients with castration-resistant prostate carcinoma

INTRODUCTION: Prostate cancer is the second most common cancer in men worldwide. When the disease becomes resistant to androgen-deprivation therapy, treatment options are sparse. To address the high medical need in castration-resistant prostate cancer (CRPC), we generated a novel PSMAxCD3 bispecific...

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Foilsithe in:BMJ Open
Main Authors: Heitmann, Jonas S, Walz, Juliane S, Pflügler, Martin, Kauer, Joseph, Schlenk, Richard F, Jung, Gundram, Salih, Helmut R
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2020
Ábhair:
Oncology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569941/
https://ncbi.nlm.nih.gov/pubmed/33067297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2020-039639
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