Detection and Therapeutic Implications of c-Met Mutations in Small Cell Lung Cancer and Neuroendocrine Tumors

BACKGROUND: We evaluated the mutation status of c-Met in small cell lung cancer (SCLC) and neuroendocrine tumors (NET), for which relatively limited therapeutic targets have been explored. MATERIALS AND METHODS: c-Met was re-sequenced using cell lines and clinical samples. For in vitro studies, DNA...

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Vydáno v:Curr Pharm Des
Hlavní autoři: Voortman, J., Harada, T., Chang, R.P., Killian, J.K., Suuriniemi, M., Smith, W.I., Meltzer, P.S., Lucchi, M., Wang, Y., Giaccone, G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569720/
https://ncbi.nlm.nih.gov/pubmed/22973954
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