Transient Receptor Potential Ankyrin-1 and Vanilloid-3 Differentially Regulate Endoplasmic Reticulum Stress and Cytotoxicity in Human Lung Epithelial Cells After Pneumotoxic Wood Smoke Particle Exposure

This study investigated the roles of transient receptor potential (TRP) ankyrin-1 (TRPA1) and TRP vanilloid-3 (TRPV3) in regulating endoplasmic reticulum stress (ERS) and cytotoxicity in human bronchial epithelial cells (HBECs) treated with pneumotoxic wood smoke particulate matter (WSPM) and chemic...

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Bibliographic Details
Published in:Mol Pharmacol
Main Authors: Nguyen, Nam D., Memon, Tosifa A., Burrell, Katherine L., Almestica-Roberts, Marysol, Rapp, Emmanuel, Sun, Lili, Scott, Abigail F., Rower, Joseph E., Deering-Rice, Cassandra E., Reilly, Christopher A.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569310/
https://ncbi.nlm.nih.gov/pubmed/32938721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/molpharm.120.000047
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