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The Role of Mast Cells in Aspirin-Exacerbated Respiratory Disease (AERD) Pathogenesis: Implications for Future Therapeutics

Mast cells (MC) have recently been demonstrated to play an integral role in the pathogenesis of aspirin-exacerbated respiratory disease (AERD). When activated, MCs release pre-formed granules of many pro-inflammatory mediators, including histamine, serotonin, and various chemokines and cytokines inc...

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Pubblicato in:J Asthma Allergy
Autori principali: Kuruvilla, Merin E, Vanijcharoenkarn, Kristine, Levy, Joshua M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569245/
https://ncbi.nlm.nih.gov/pubmed/33116654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S237463
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