A bioengineered organotypic prostate model for the study of tumor microenvironment-induced immune cell activation

The prostate tumor microenvironment (TME) is strongly immunosuppressive; it is largely driven by alteration in cell phenotypes (i.e. tumor-associated macrophages and exhausted cytotoxic T cells) that result in pro-tumorigenic conditions and tumor growth. A greater understanding into how these altere...

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Bibliographic Details
Published in:Integr Biol (Camb)
Main Authors: Kerr, Sheena C, Morgan, Molly M, Gillette, Amani A, Livingston, Megan K, Lugo-Cintron, Karina M, Favreau, Peter F, Florek, Logan, Johnson, Brian P, Lang, Joshua M, Skala, Melissa C, Beebe, David J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7569006/
https://ncbi.nlm.nih.gov/pubmed/33034643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intbio/zyaa020
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