Phase I trial evaluating safety and efficacy of intratumorally administered inflammatory allogeneic dendritic cells (ilixadencel) in advanced gastrointestinal stromal tumors

BACKGROUND: The majority of patients with advanced gastrointestinal stromal tumor (GIST) develop resistance to imatinib, and subsequent treatments have limited efficacy. Ilixadencel (allogeneic inflammatory dendritic cells) is a cell-based immune primer injected intratumorally that previously has be...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Fröbom, Robin, Berglund, Erik, Berglund, David, Nilsson, Inga-Lena, Åhlén, Jan, von Sivers, Karin, Linder-Stragliotto, Christina, Suenaert, Peter, Karlsson-Parra, Alex, Bränström, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568699/
https://ncbi.nlm.nih.gov/pubmed/32535637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02625-5
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