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Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin

Global emergence of Gram-negative bacteria carrying the plasmid-borne resistance genes, bla(MBL) and mcr, raises a significant challenge to the treatment of life-threatening infections by the antibiotics, carbapenem and colistin (COL). Here, we identify an antirheumatic drug, auranofin (AUR) as a du...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sun, Hongzhe, Zhang, Qi, Wang, Runming, Wang, Haibo, Wong, Yuen-Ting, Wang, Minji, Hao, Quan, Yan, Aixin, Kao, Richard Yi-Tsun, Ho, Pak-Leung, Li, Hongyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568570/
https://ncbi.nlm.nih.gov/pubmed/33067430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18939-y
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