Non-invasive detection of EGFR mutations by cell-free loop-mediated isothermal amplification (CF-LAMP)

Targeting epidermal growth factor receptor (EGFR) through tyrosine kinase inhibitors (TKI) is a successful therapeutic strategy in non-small cell lung cancer. However, the response to TKI therapy depends on specific activating and acquired mutations in the tyrosine kinase domain of the EGFR gene. Th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Arjuna, Srividya, Venkataram, Rajesh, Dechamma, Pandyanda Nanjappa, Chakraborty, Gunimala, Babu, Nishith, D’Cruz, Audrey, Hosmane, Giridhar Belur, Chakraborty, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568567/
https://ncbi.nlm.nih.gov/pubmed/33067539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74689-3
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