A carregar...
Hematopoietic gene therapy restores thymidine phosphorylase activity in a cell culture and a murine model of MNGIE
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder caused by mutations in the TYMP gene, which encodes thymidine phosphorylase (TP). TP dysfunction results in systemic thymidine (dThd) and deoxyuridine (dUrd) overload, which selectively impair mitochondr...
Na minha lista:
| Publicado no: | Gene Ther |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568345/ https://ncbi.nlm.nih.gov/pubmed/21451581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.24 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|