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Converting Escherichia coli MG1655 into a chemical overproducer through inactivating defense system against exogenous DNA

Escherichia coli strain K-12 MG1655 has been proposed as an appropriate host strain for industrial production. However, the direct application of this strain suffers from the transformation inefficiency and plasmid instability. Herein, we conducted genetic modifications at a serial of loci of MG1655...

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Detalhes bibliográficos
Publicado no:Synth Syst Biotechnol
Main Authors: Wang, Jingge, Huang, Chaoyong, Guo, Kai, Ma, Lianjie, Meng, Xiangyu, Wang, Ning, Huo, Yi-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568196/
https://ncbi.nlm.nih.gov/pubmed/33102829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.synbio.2020.10.005
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