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Naught all zeros in sequence count data are the same

Genomic studies feature multivariate count data from high-throughput DNA sequencing experiments, which often contain many zero values. These zeros can cause artifacts for statistical analyses and multiple modeling approaches have been developed in response. Here, we apply different zero-handling mod...

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Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteurs principaux: Silverman, Justin D., Roche, Kimberly, Mukherjee, Sayan, David, Lawrence A.
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568192/
https://ncbi.nlm.nih.gov/pubmed/33101615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.09.014
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