Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE

Oxidative stress (OS) and neuronal apoptosis are major pathological processes after hypoxic-ischemic encephalopathy (HIE). Colony stimulating factor 1 (CSF1), binding to CSF1 receptor (CSF1R), has been shown to reduce neuronal loss after hypoxic-ischemia- (HI-) induced brain injury. In the present s...

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Библиографические подробности
Опубликовано в: :Oxid Med Cell Longev
Главные авторы: Hu, Xiao, Li, Shirong, Doycheva, Desislava Met, Huang, Lei, Lenahan, Cameron, Liu, Rui, Huang, Juan, Gao, Ling, Tang, Jiping, Zuo, Gang, Zhang, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568161/
https://ncbi.nlm.nih.gov/pubmed/33101590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6801587
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