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Dimerization of SERCA2a Enhances Transport Rate and Improves Energetic Efficiency in Living Cells
The type 2a sarco/endoplasmic reticulum (ER) Ca(2+)-ATPase (SERCA2a) plays a key role in intracellular Ca(2+) regulation in the heart. We have previously shown evidence of stable homodimers of SERCA2a in heterologous cells and cardiomyocytes. However, the functional significance of the pump dimeriza...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567987/ https://ncbi.nlm.nih.gov/pubmed/32946770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.025 |
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