Glycolytic competence in gastric adenocarcinomas negatively impacts survival outcomes of patients treated with salvage paclitaxel-ramucirumab

INTRODUCTION: For energy production, cancer cells maintain a high rate of glycolysis instead of oxidative phosphorylation converting glucose into lactic acid. This metabolic shift is useful to survive in unfavorable microenvironments. We investigated whether a positive glycolytic profile (PGP) in ga...

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Vydáno v:Gastric Cancer
Hlavní autoři: Ruzzo, Annamaria, Graziano, Francesco, Bagaloni, Irene, Di Bartolomeo, Maria, Prisciandaro, Michele, Aprile, Giuseppe, Ongaro, Elena, Vincenzi, Bruno, Perrone, Giuseppe, Santini, Daniele, Fornaro, Lorenzo, Vivaldi, Caterina, Tomasello, Gianluca, Loupakis, Fotios, Lonardi, Sara, Fassan, Matteo, Valmasoni, Michele, Sarti, Donatella, Lorenzini, Paola, Catalano, Vincenzo, Bisonni, Renato, Del Prete, Michela, Collina, Guido, Magnani, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567716/
https://ncbi.nlm.nih.gov/pubmed/32372141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10120-020-01078-0
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