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CXCR4 expression in the bone marrow microenvironment is required for hematopoietic stem and progenitor cell maintenance and early hematopoietic regeneration after myeloablation

The bone marrow microenvironment/niche plays a key role in regulating hematopoietic stem and progenitor cell (HSPC) activities, however mechanisms regulating niche cell function are not well understood. In this study, we show that niche intrinsic expression of the CXCR4 chemokine receptor critically...

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Bibliografski detalji
Izdano u:Stem Cells
Glavni autori: Singh, Pratibha, Mohammad, Khalid S., Pelus, Louis M.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566894/
https://ncbi.nlm.nih.gov/pubmed/32159901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3174
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