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GPR101 Mutations are not a frequent cause of Congenital Isolated Growth Hormone Deficiency
OBJECTIVE: Patients with Xq26.3 microduplication present early-childhood gigantism due to marked growth hormone (GH) hypersecretion from mixed GH-PRL adenomas and hyperplasia. The microduplication includes GPR101 which is upregulated in patients’ tumor tissue. The GPR101 gene codes for an orphan G p...
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Publicado no: | Horm Metab Res |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566854/ https://ncbi.nlm.nih.gov/pubmed/26797872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0042-100733 |
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