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αβDCA method identifies unspecific binding but specific disruption of the group I intron by the StpA chaperone

Chaperone proteins—the most disordered among all protein groups—help RNAs fold into their functional structure by destabilizing misfolded configurations or stabilizing the functional ones. But disentangling the mechanism underlying RNA chaperoning is challenging, mostly because of inherent disorder...

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Bibliografische gegevens
Gepubliceerd in:RNA
Hoofdauteurs: Reinharz, Vladimir, Tlusty, Tsvi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566574/
https://ncbi.nlm.nih.gov/pubmed/32747608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.074336.119
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