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Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis
Numb is a negative regulator of Notch signal pathway. Previous study has demonstrated that Notch signal pathway activation is required for hepatic progenitor cell (HPC) differentiating into cholangiocytes in cholestatic liver fibrosis (CLF), and Huang Qi Decoction (HQD) could prevent CLF through inh...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566460/ https://ncbi.nlm.nih.gov/pubmed/33060633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74324-1 |
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