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Choice of Differentiation Media Significantly Impacts Cell Lineage and Response to CFTR Modulators in Fully Differentiated Primary Cultures of Cystic Fibrosis Human Airway Epithelial Cells

In vitro cultures of primary human airway epithelial cells (hAECs) grown at air–liquid interface have become a valuable tool to study airway biology under normal and pathologic conditions, and for drug discovery in lung diseases such as cystic fibrosis (CF). An increasing number of different differe...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Saint-Criq, Vinciane, Delpiano, Livia, Casement, John, Onuora, Jennifer C., Lin, JinHeng, Gray, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565948/
https://ncbi.nlm.nih.gov/pubmed/32967385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092137
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