Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy

Temporal lobe epilepsy (TLE), the most common type of focal epilepsy, affects learning and memory; these effects are thought to emerge from changes in synaptic plasticity. Levetiracetam (LEV) is a widely used antiepileptic drug that is also associated with the reversal of cognitive dysfunction. The...

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Veröffentlicht in:Brain Sci
Hauptverfasser: González-H, Guillermo, Contreras-García, Itzel Jatziri, Sánchez-Huerta, Karla, Queiroz, Claudio M. T., Gallardo Gudiño, Luis Ricardo, Mendoza-Torreblanca, Julieta G., Zamudio, Sergio R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565946/
https://ncbi.nlm.nih.gov/pubmed/32933015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci10090634
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