A new mouse model to study restoration of interleukin-6 (IL-6) expression in a Cre-dependent manner: microglial IL-6 regulation of experimental autoimmune encephalomyelitis

BACKGROUND: Interleukin-6 (IL-6) is a pleiotropic cytokine that controls numerous physiological processes both in basal and neuroinflammatory conditions, including the inflammatory response to experimental autoimmune encephalomyelitis (EAE). IL-6 is produced by multiple peripheral and central cells,...

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Publicat a:J Neuroinflammation
Autors principals: Sanchis, Paula, Fernández-Gayol, Olaya, Comes, Gemma, Aguilar, Kevin, Escrig, Anna, Giralt, Mercedes, Palmiter, Richard D., Hidalgo, Juan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565836/
https://ncbi.nlm.nih.gov/pubmed/33059703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01969-0
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