RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis

Epithelial remodeling involves ratcheting behavior whereby periodic contractility produces transient changes in cell-cell contact lengths, which stabilize to produce lasting morphogenetic changes. Pulsatile RhoA activity is thought to underlie morphogenetic ratchets, but how RhoA governs transient c...

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Udgivet i:Dev Cell
Main Authors: Cavanaugh, Kate E., Staddon, Michael F., Munro, Edwin, Banerjee, Shiladitya, Gardel, Margaret L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565439/
https://ncbi.nlm.nih.gov/pubmed/31883774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.12.002
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