A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21

Leptospirosis vaccines with higher potency and reduced adverse effects are needed for human use. The carboxyl terminal domain of leptospiral immunoglobulin like protein A (LigAc) is currently the most promising candidate antigen for leptospirosis subunit vaccine. However, LigAc-based vaccines were u...

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Publicado no:Vaccines (Basel)
Main Authors: Techawiwattanaboon, Teerasit, Barnier-Quer, Christophe, Palaga, Tanapat, Jacquet, Alain, Collin, Nicolas, Sangjun, Noppadon, Komanee, Pat, Patarakul, Kanitha
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565420/
https://ncbi.nlm.nih.gov/pubmed/32882903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030494
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