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The FMS like Tyrosine Kinase 3 (FLT3) Is Overexpressed in a Subgroup of Multiple Myeloma Patients with Inferior Prognosis

Therapy resistance remains a major challenge in the management of multiple myeloma (MM). We evaluated the expression of FLT3 tyrosine kinase receptor (FLT3, CD135) in myeloma cells as a possible clonal driver. FLT3 expression was analyzed in bone marrow biopsies of patients with monoclonal gammopath...

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Dades bibliogràfiques
Publicat a:Cancers (Basel)
Autors principals: Steiner, Normann, Jöhrer, Karin, Plewan, Selina, Brunner-Véber, Andrea, Göbel, Georg, Nachbaur, David, Wolf, Dominik, Gunsilius, Eberhard, Untergasser, Gerold
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565188/
https://ncbi.nlm.nih.gov/pubmed/32825035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092341
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