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Tryptophanyl-tRNA Synthetase 1 Signals Activate TREM-1 via TLR2 and TLR4
Tryptophanyl-tRNA synthetase 1 (WARS1) is an endogenous ligand of mammalian Toll-like receptors (TLR) 2 and TLR4. Microarray data, using mRNA from WARS1-treated human peripheral blood mononuclear cells (PBMCs), had indicated WARS1 to mainly activate innate inflammatory responses. However, exact mole...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7565148/ https://ncbi.nlm.nih.gov/pubmed/32899943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091283 |
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