Canonical and Noncanonical Roles of Fanconi Anemia Proteins: Implications in Cancer Predisposition

SIMPLE SUMMARY: Fanconi anemia (FA) is a genetic disorder that is characterized by bone marrow failure (BMF), developmental abnormalities, and predisposition to cancer. In this review, we present an overview of both canonical (regulation of interstrand cross-links repair, ICLs) and noncanonical role...

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Publicat a:Cancers (Basel)
Autors principals: Milletti, Giacomo, Strocchio, Luisa, Pagliara, Daria, Girardi, Katia, Carta, Roberto, Mastronuzzi, Angela, Locatelli, Franco, Nazio, Francesca
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565043/
https://ncbi.nlm.nih.gov/pubmed/32962238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092684
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