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STAT3, the Challenge for Chemotherapeutic and Radiotherapeutic Efficacy

SIMPLE SUMMARY: STAT3, an oncogene, contributes to insensitivity of chemotherapy and radiotherapy in tumor, reduces the clinical efficacy. Meanwhile, STAT3β, a STAT3 splicing isoform, is related to the inhibition of tumor growth and chemosensitivity. STAT3 may become a potential target to overcome t...

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發表在:Cancers (Basel)
Main Authors: Yang, Ping-Lian, Liu, Lu-Xin, Li, En-Min, Xu, Li-Yan
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564975/
https://ncbi.nlm.nih.gov/pubmed/32872659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092459
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