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5-aza-2′-Deoxycytidine Induces a RIG-I-Related Innate Immune Response by Modulating Mitochondria Stress in Neuroblastoma

Background: Neuroblastoma (NB) is one of the most common malignant solid tumors to occur in children, characterized by a wide range of genetic and epigenetic aberrations. We studied whether modifications of the latter with a 5-aza-2′-deoxycytidine (decitabine, Dac) DNA methyltransferase inhibitor ca...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Lin, Hung-Yu, Chuang, Jiin-Haur, Wang, Pei-Wen, Lin, Tsu-Kung, Wu, Min-Tsui, Hsu, Wen-Ming, Chuang, Hui-Ching
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564572/
https://ncbi.nlm.nih.gov/pubmed/32824929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091920
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