IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice

The Th2 cytokine IL-13 is involved in biliary epithelial injury and liver fibrosis in patients as well as in animal models. The aim of this study was to investigate IL-13 as a therapeutic target during short term and chronic intrahepatic cholestasis in an Abcb4-knockout mouse model (Abcb4(−/−)). Lac...

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Publicado no:Cells
Main Authors: Hahn, Luisa, Helmrich, Nora, Herebian, Diran, Mayatepek, Ertan, Drebber, Uta, Domann, Eugen, Olejniczak, Stefan, Weigel, Markus, Hain, Torsten, Rath, Timo, Wirtz, Stefan, Mollenkopf, Hans-Joachim, Schmidt, Nadine, Ewers, Christa, Baier, Anne, Churin, Yuri, Windhorst, Anita, Weiskirchen, Ralf, Steinhoff, Ulrich, Roeb, Elke, Roderfeld, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564366/
https://ncbi.nlm.nih.gov/pubmed/32846954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091949
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