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Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells

De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may predict chemotherapy response in vitro. Whether exon-v6 itself is responsible for conferring these properties to CD44v6-containing isoforms remains to be elucidated. CRISPR/C...

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Publicat a:Cancers (Basel)
Autors principals: Lobo, Silvana, Pereira, Carla, Oliveira, Carla, Almeida, Gabriela M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564355/
https://ncbi.nlm.nih.gov/pubmed/32842638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092378
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